Vanessa Giselle was born in Iowa City, Iowa. She is best known for her role on FX's Mayans M.C. (2019-2023), in which she portrays a sensitive and hurting heroin abuser named Hope. She is also known for her recurring role on the popular Starz series VIDA (2020), and has made appearances on shows such as FX's Sons of Anarchy and Showtime's Shameless.