South African-born Thuso graduated from the National Institute of Dramatic Art at the end of 2014, snaring his first acting role immediately after graduation with the Kriv Stenders directed television drama The Principal. He then appeared in his first feature 2:22, an American-Australian thriller, as well as Aquarius Films' feature Berlin Syndrome and the television series Random and Whacky for Ambience Entertainment. Thuso hosted the children's television program Imagination Train and has narrated several programs for ABC Radio. The premiere of Prize Fighter at Brisbane Festival in 2015 marked his debut theatre performance, with Thuso garnering a Helpmann Award nomination for Best Actor in a Supporting Role. He re-created this role in the Belvoir production in 2016. Last year saw Thuso play the role of 'Malcolm' in Bell Shakespeare's production of Macbeth. Thuso has most recently performed in Belvoir's A Taste of Honey, Darlinghurst Theatre's The Mystery of Love and Sex, appeared in the ABC's medical drama Pulse and completed filming on the Heath Davis directed feature film Book Week